During an interview for GamerLiveTV, Nintendo executive Scott Moffit gave a slight hint at a possible Metroid game for Nintendo’s new console, Wii U:
With Metroid Blast, you get to enjoy that franchise while the developers are, you know, thinking and imagining what could be possible with Metroid on Wii U.
He also said something similar about The Legend of Zelda series and its Nintendo Land minigame The Legend of Zelda: Battle Quest, mentioning that “all can’t wait to see what a Zelda experience might look like in high definition” and “there could be a lot of new features added with the GamePad.”
While the quote doesn’t confirm that Metroid is actually in development for Wii U, it shows that the possibility for a new entry is certainly there.
Source: GamerLiveTV (quotes are near end of the video)